Joining forces in substantiating health benefits

Human Challenge Models to Accelerate Health Benefits Development

7 June 2017

NIZO, Royal FrieslandCampina and Nutrileads are joining forces in the CHALLENGE consortium. CHALLENGE aims to develop new food ingredients that will support resistance to infections, as well as affordable and predictive research models in healthy volunteers to allow companies accelerated market access.

Alwine Kardinaal, project leader at NIZO: ‘The combined research power of the companies involved is unique and will enable us to take the next step in predicting health benefits with the use of Human Challenge Studies. Especially in nutrition research, challenge studies are a unique approach to induce a physiological response in healthy subjects and to investigate how an active ingredient modulates this response. Given NIZO’s reputation with i.e. the ETEC model, we are confident to lead this exciting project.’

Ruud Albers, CEO of Nutrileads: ‘Nutrileads strongly believes in the Human Challenge Model concept. The CHALLENGE consortium is a logical next step in substantiating the immune supportive effect of our lead ingredient, a novel Immune Modulating Plant Polysaccharide.’

Marjolijn Bragt, research leader at FrieslandCampina explains: ‘FrieslandCampina wants to contribute towards feeding the world population and focuses on improving its products to contribute to the consumer needs. The innovative power of CHALLENGE is expressed in the evaluation of translational biomarkers for infants and children.’

The CHALLENGE project has a total budget of 3.7 million Euro, of which 1.5 million Euro will be co-financed by the European Union and EFRO OP-Oost. The subsidy was granted in Q2 2017; first results will become available later this year.